Is azithromycin like clindemycin

azithromycin clindemycin is like

Jump to navigation. This review aimed to assess whether the treatment of chlamydial infection during pregnancy cured the infection and prevented complications to the women and babies without causing side effects. Azithromycin like new review supersedes an earlier review on this topic. Chlamydia trachomatis is a bacterial infection which is sexually transmitted.

It is more common in younger women. Women may have the infection without knowing it. In clindemycin women, clindemycin Chlamydia trachomatis can cause pregnancy complications such as preterm labour, preterm birth, premature rupture of the membranes, low birthweight of infants, and infection clindemycin the uterus after giving like clindemycin azithromycin is. Babies who acquire Chlamydia trachomatis during birth can develop infection of the lungs and the eyes.

Finding an effective treatment with minimal side effects is extremely important considering the complications that can occur with untreated Chlamydia trachomatis infection in pregnancy. We searched for evidence June and included 15 studies in the review. The studies had a mixed risk of bias and were of limited quality, often with small numbers of participants. Three studies compared antibiotics erythromycin, clindamycin, and amoxicillin with placebo.

The other studies compared different antibiotics with each other. All of the studies reported on curing chlamydia, based on the elimination of the bacteria, with an antibiotic. Erythromycin moderate-quality evidence from two studies, women and clindamycin low-quality evidence from one study85 women appeared to be more effective than placebo.

The quality of the evidence for amoxicillin versus placebo one study 15 women was very low so we cannot be certain of the results. When comparing different antibiotics with each other, no one antibiotic was substantially better than another at curing chlamydia in the studies that we examined: Only single trials assessed repeated infections, preterm birth, preterm rupture of membranes, perinatal mortality and low birthweight and found there were no clear differences between the different types of antibiotics examined.

Side effects were clindemycin common with erythromycin two studies, women and clindamycin one study85 women than with placebo. Amoxicillin resulted in fewer side effects than azithromycin one study36 women or erythromycin four studies, womenand azithromycin caused fewer side effects than erythromycin six studies, women. Amoxicillin and clindamycin produced a similar number of side effects in one study women.

Tramadol to help with opiate withdrawal does this mean? Treatment of chlamydia infection with antibiotics appears to be effective during pregnancy. There is no clear difference between amoxicillin, erythromycin, clindamycin, azithromycin in curing the infection or preterm birth, preterm rupture of membranes, and low birthweight. Azithromycin and clindamycin appear clindemycin result in fewer side effects than erythromycin.

The included studies were all carried out in North America. Chlamydia testing remains a problem in low-resource settings because of its costs. We conclude that well-designed studies of appropriate sample size, in different settings, are needed to further assess the clindemycin of treatment of chlamydia "like clindemycin azithromycin is" in pregnancy. Resistance to the tested antibiotics could have changed since the studies included in this review were soma tramadol and xanax. In particular, future research could report on the outcomes of focus in this review and target those antibiotics, such as amoxicillin and clindamycin, which may be effective in curing chlamydia with the least side effects.

Treatment with antibacterial agents achieves microbiological cure from C. There was no apparent difference between assessed agents amoxicillin, erythromycin, clindamycin, azithromycin in terms of efficacy microbiological cure and repeat infection and pregnancy complications preterm birth, preterm rupture of membranes, low birthweight. All of the studies in this review were conducted in North America, which may limit the generalisability of the results.

In addition, study populations may differ in low-resource settings and these results are therefore only applicable to well-resourced settings. Furthermore, the trials in this review mainly took place in the nineties and early 's and antibiotic resistance may have changed since then. Further well-designed studies, with appropriate sample sizes and set in a variety of settings, are required to further evaluate interventions for treating C.

Such studies could report on the outcomes listed clindemycin this review. Genital Chlamydia trachomatis C. This review supersedes a previous review on this topic. To establish the most efficacious and best-tolerated therapy for treatment of genital chlamydial infection in preventing maternal infection and adverse neonatal outcomes. Randomised controlled trials RCTs as well as studies published in abstract form assessing interventions for treating genital C.

Cluster- RCTs were also eligible for inclusion but none were identified. Quasi-randomised trials and trials using cross-over design are not eligible for inclusion in this review. Two review authors independently assessed studies for inclusion, assessed trial clindemycin and extracted the data using the agreed form. Data were checked for accuracy. All of the included studies were "clindemycin" in North America from to Two studies were low risk of bias in all domains, all other studies had varying risk of bias.

Four other studies were excluded and one study is ongoing. Eight comparisons were included in this review ; three compared antibiotic erythromycin, clindamycin, amoxicillin versus placebo ; five compared an antibiotic versus another antibiotic erythromycin, clindamycin, amoxicillin, azithromycin. No clindemycin reported different drug interaction hydrocodone and xanax regimens.

Microbiological cure primary outcome. Antibiotics versus placebo: Erythromycin average risk ratio RR 2. In one very small trial comparing amoxicillin and placebothe results were unclear, but the evidence was graded very low RR 2. One antibiotic versus another antibiotic: Amoxicillin made little or no difference in microbiological cure in comparison to erythromycin RR 0. Azithromycin versus erythromycin average RR 1. Clindamycin versus erythromycin RR 1. Evidence was downgraded for design limitations, inconsistency, and imprecision in effect estimates.

Side effects of the treatment maternal secondary outcome. The side effects reported order phentermine online cheap mostly gastrointestinal and also included resolving skin rashes. There was no clear difference in incidence of side effects including nausea, vomiting, diarrhoea and abdominal pain when amoxicillin was compared to azithromycin based on data from one small study 36 women RR 0.

However, xanax dosage severe anxiety was associated with fewer side effects compared to erythromycin with clindemycin from four trials women RR 0. Side effects included nausea, vomiting, diarrhoea, abdominal cramping, rash, and allergic reaction. Both azithromycin RR 0. These side effects included nausea, vomiting, diarrhoea and abdominal cramping. One small study women reported there was clindemycin clear difference in the number of women with side effects when amoxicillin was compared with clindamycin RR 0.

The side effects reported included rash and gastrointestinal ambien side effects acne. Single trials reported data on repeated infections, preterm birth, preterm rupture of membranes, perinatal mortality and low birthweight and found no clear clindemycin between treatments. Many of this review 's secondary outcomes were not reported in the included studies.

Treatment of genital Chlamydia trachomatis infection in pregnancy What is the issue? Why is this important? What evidence did we find? Authors' conclusions: Search strategy: Selection criteria: Data collection and analysis: Main results: Microbiological cure primary outcome Antibiotics versus placebo: Side effects of the treatment maternal secondary outcome Antibiotics versus placebo: Other secondary outcomes Single trials reported data clindemycin repeated infections, preterm birth, preterm rupture of membranes, perinatal mortality and low birthweight and found no clear differences between treatments.

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